Deoxypodophyllotoxin (DPT) is a potential anti-tumor candidate prior to its clinical phase. The aim of the study was to develop a physiologically-based pharmacokinetic (PBPK) model consisting of 13 tissue compartments to predict DPT disposition in mouse. rat. monkey and dog based on in vitro and in silico inputs. https://missouriquiltcoes.shop/product-category/collections/