Sildenafil Boosts the outcome of NO by inhibiting phosphodiesterase form 5 (PDE5), which happens to be liable for degradation of cGMP during the corpus cavernosum. Sildenafil has no immediate relaxant impact on isolated human corpus cavernosum. Hemic and Lymphatic: vaso-occlusive crisis: In a small, prematurely terminated review of REVATIO (sildenafil) https://janestevensnutrition.com